Serological, biochemical and enzymatic alterations in rodents after experimental envenomation with Hadruroides lunatus scorpion venom

Effectiveness of anti scorpion venom for red scorpion envenomation.

OBJECTIVE To study the efficacy of anti-scorpion venom plus prazocin. METHODS Comparison of clinical features, outcome and duration of stay between children receiving anti-scorpion venom plus prazocin or prazocin alone for management of red scorpion envenomation. RESULTS Requirement for dopamine and requirement and duration of dobutamine therapy were significantly less in patients received ...

Biochemical and Histopathological study of Mesobuthus eupeus scorpion venom in the experimental rabbits

In tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. In the present study, the toxic effects of mice LD50 injections of Mesobuthus eupeus (Me) venom on the kidney and liver of anesthetized rabbits were investigated. Six rabbits were selected and ALT, AST, BUN and creatinine were measured at 0, 1 and 3 hours after...

Scorpion Venom Pisoning in Experimental Animals

ANTIVENOM REVERSAL OF BIOCHEMICAL ALTERATIONS INDUCED BY BLACK SCORPION Heterometrus fastigiousus COUZIJN VENOM IN MICE

In the present study, Heterometrus fastigiousus venom (HFV) was employed as antigen to produce species-specific scorpion antivenom (SAV) in albino mice (NIH) strain. To determine SAV efficacy, it was pre-incubated with 10 LD50 of HFV and then injected subcutaneously into mice. Subsequently, mortality was observed after 24 hours. Minimum effective dose (MED) was 12.5 LD50 of HFV/mL of SAV. SAV e...

Haemodynamic patterns in patients with scorpion envenomation.

OBJECTIVE To study cardiovascular haemodynamics following scorpion envenomation. SETTING Intensive care unit of a university hospital. PATIENTS Eight patients with Indian red scorpion (Mesobuthus tamulus) stings. INTERVENTION Captopril (6.25 to 12.5 mg orally) every 30 minutes until pulmonary oedema resolved. MAIN OUTCOME MEASURES Haemodynamic data obtained by pulmonary artery catheteri...